Microbial Identification System (MALDI-TOF MS) (Bruker)
Product Name Microbial Identification System (MALDI-TOF MS)
Model Name Bruker MALDI Biotyper® sirius System
Brand Name Bruker Daltonics
Country of Origin Germany
Bruker MALDI Biotyper® System – Rapid Microbial Identification
The Bruker MALDI Biotyper® System is a MALDI-TOF mass spectrometry platform for rapid microbial identification in clinical microbiology laboratories. It identifies microorganisms by generating a unique proteomic fingerprint spectrum and matching it against an extensive reference library, enabling species-level identification within minutes after culture.
The MALDI Biotyper® is widely used for routine identification of clinically relevant microorganisms, including Gram-positive and Gram-negative bacteria, anaerobes, yeasts, and filamentous fungi. Fast identification supports timely clinical decision-making and antimicrobial stewardship by enabling earlier optimization of therapy based on accurate organism identification.
General Description – MALDI Biotyper® sirius System
The MALDI Biotyper® sirius System represents the latest fourth-generation evolution of Bruker’s benchtop MALDI Biotyper® platform. The system integrates a high-performance vacuum system and Bruker’s proprietary smartbeam™ lifetime laser technology to support stable, high-throughput routine operation. The sirius platform is designed for fast target exchange and efficient workflows, enabling swift analysis for increasing laboratory demands.
Product Description – Overview
| Feature | Description |
| Technology | - MALDI-TOF Mass Spectrometry |
| Identification Principle | - Proteomic fingerprint matching to a reference library |
| Time to Result | - Identification within minutes after culture |
| Identification Coverage | - More than 4,600 validated microbial species / species groups (library coverage varies by configuration and updates) |
| Throughput | - Swift analysis of up to 600 samples per hour (platform capability) |
| Laser System | - smartbeam™ lifetime laser (designed for extended routine use) |
| Vacuum System | - High-performance vacuum system for fast target exchange |
| Microorganism Types | - Gram-positive and Gram-negative bacteria, anaerobes, yeasts and filamentous fungi |
| Workflow | - Simple colony-based workflow; dedicated workflows available for specific applications |
Key Advantages
• Gold-standard MALDI-TOF technology for rapid microbial identification
• Ultra-fast identification within minutes after culture
• Broad reference library coverage supporting routine and advanced microbiology
• High-throughput capability suitable for busy laboratories
• Fourth-generation benchtop sirius platform with smartbeam™ lifetime laser and high-performance vacuum
• Supports faster reporting to enable improved clinical decision-making and antimicrobial stewardship
Regulatory & Quality
• Available in Research Use Only (RUO) and In Vitro Diagnostic (IVD) configurations, depending on country regulations
• IVD configuration: qualitative in vitro diagnostic MALDI-TOF mass spectrometer for clinical use, supplied with IVD software, reference libraries, reagents and workflows
• Manufacturer quality system: ISO 13485 compliant (where applicable per configuration)
• Professional use only